Alexander the Great. He definitely has had the most impact. He is probably one of the earliest figures to have connected the west (Europe) with the east (India, Persia).
He was very tolerant of the Persians. It was at a time when the Greeks used to loathe Persians. After Xerxes invaded and plundered Greece in 479 BC, Alexander was the one who tool their revenge in 330 BC, by burning the Persian capital down to ruins.
This was at a time when society was very close to each other and folks didn't used to forget what their ancestors had to go through (whwt the invaders did basically).
The Greeks were extremely happy to have crushed Persians and celebrated. If Alexander wanted, he could've gotten the Persians executed, which would surely have further cemented his legacy. But he chose to forgive them (not easy for him).
He administered the Persians into his army and won Egypt, far eastern provinces of Persia where he eventually married a Bactrian Princess, and also invaded India with Persian horse archers.
He very well knew that his life would've been in danger by treating Persians well (Greeks weren't happy) and administering Persians in his army was anyway going to be challenging (Alexander was hated by patriotic Persians). But still he did.
He also ensured his fellow Greek generals would marry Persian princes in a grand mass wedding to ensure ties get more stronger between east and the west.
He really did a lot.
He is truly Aledander the Great.
Reiterating, he did this in 330 BCE, just take a moment to grasp the societal and other cultural differences.