Seeing the S&P500 witness a spectacular "short" rally before popping, and then it becoming decidedly clear that even if the rate hikes were unlikely it was still going to be a long time before rates come down. Becoming much more clearer that the impact on various asset classes and securities is going to be muted for the time to be.
Unless interest rates come down, I can't possibly imagine that the VC funding will pick up again, their LPs can't put in more money unless interest rates come down. Cheap capital fuels the VC ecosystem, if capital isn't cheap then allocation in VC Funds goes down to adjust to a newly adjusted risk appetite of investors.