In the initial rounds itself I would check for the fundamentals.
say for frontend, i would check for plain html, css and javascript, take points from resume, talk indepth about them, simple html css responsive page.
Looks simple but most of them fail to answer these itself coz nowadays everyone focuses on writing react only that too at the very base level itself.
Backend- cpu, process, middleware, database queries.
In past couple of years talent of folks has gone up multiple times so depends on company I am interviewing for and have come across freshers who would beat me with their knowledge levels when I had say 4 years of work exp.