We should never worry about drugs a.k.a medicines for weight loss when you could just get on a proper diet routine avoiding junk food, having good sleep cycles and exercising frequently if not regularly.

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Scientists are exploring the potential of obesity drugs to treat various ailments, from alcoholism to Parkinson's disease.  GLP1 receptor agonists, a class of weightloss drugs, show promise in redu...

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- Scientists are exploring the potential of obesity drugs to treat various ailments, from alcoholism to Parkinson's disease.
- GLP-1 receptor agonists, a class of weight-loss drugs, show promise in reducing cravings for substances like alcohol and tobacco.
- These drugs may also lower the risk of cardiovascular events, ease sleep apnea, and slow the progression of neurodegenerative diseases.
- Researchers are still trying to understand the mechanisms behind these benefits, which may involve both weight loss and anti-inflammatory effects.
- Despite the excitement, experts caution against viewing these drugs as a universal cure, especially given unknown long-term effects. 

 Source: [Nature](https://www.nature.com/articles/d41586-024-03074-1)

Obesity Drugs: Miracle Cure or Overhyped Solution?

Journalist

Obesity Drugs: Miracle Cure or Overhyped Solution?- Grapevine

Obesity is the biggest killer. Epidemic which has impacted every country. I’m quite bullish on some major breakthroughs in this decade. 

Hope more companies spend more r&d $$s on it. And make it accessible to masses across the world.

Some serious work going on in the world weight loss drugs

Software Developer

- Scientists are starting to unravel the secrets behind Ozempic/Wegovy and similar GLP-1 drugs.
- New trial data shows GLP-1 therapy can boost the body’s fat-burning potential, not just reduce appetite.
- The study, conducted in Ireland, involved 30 patients with obesity and obstructive sleep apnea.
- Results indicated that people on liraglutide experienced a significant increase in their ability to burn off visceral fat.
- Researchers emphasize the need for more studies to confirm these findings and explore newer, more effective GLP-1 drugs. 

 Source: [Gizmodo](https://gizmodo.com/does-ozempic-burn-fat-or-just-reduce-appetite-a-new-study-offers-a-clue-2000489865)

Does Ozempic Burn Fat or Just Reduce Appetite? A New Study Offers a Clue

Had a regular yearly check up 2 weeks back and found that I'm diabetic. Both my parents are diabetic and I assumed I'll be as well at some point in my life as an inheritance from them but never thought this early. I did not tell this to anyone, not even my wife. Took me 2 weeks to get hold of myself and let the feeling sink in.
Started making changes to my life style since yesterday and started working out as well. Today is Day-2.

Health scare at 35

My Experience:

2 years back I was detected Pre-diabetic. Cut down consumption of white sugar to zero. Cut down on any food that has White Sugar in it (Biscuits, Ice Cream, Desserts, cold drinks, etc.). Became conscious of reading ingedrients/Contain's part when I buy any packed food. 

Developed habit of walking 8K steps or burning 150Kcal after dinner. My glycemic levels are now normal. I am no longer a pre-diabetic. This can be managed with active lifestyle. White sugar is a poison. Rely on Fruits to fulfill the glucose levels of your body. 

PS: After 2 years I've started consuming food having white sugar occasionally ( on Diwali or Holi and that too in limits). Never restricted myself from consuming naturally sweet fruits (Banana, Mango, Apple, etc.).

Product Manager

Why do relatives feel that they should always talk about doing things the right way and how do they know what they say is the right way?

Some examples -
- to lose weight, focus on walking and fully come to normal BMI and then only do weight training. But, research suggests weight training to be more beneficial for both weight loss and increasing metabolism
- we should drink hot water to lose weight. What?😂
- get married early and marriage is the only way to go!
- our screen time shouldn't be more with mobile, but rather with tv
- don't use earphones, they damage ears
- Some fruits are beneficial for diabetes

Don't get me wrong, I love relatives. I just don't enjoy someone giving advice when I didn't ask them. Especially when I can't trust their source of information for anything - life advices, religion, shastra,  traditions, women's rights etc.

And, I am really tired fighting battle and tackling so much misinformation about everything. All I do is just listen to them and move on!

Wanted to know what do you guys do?

How do you deal with unsolicited advice of relatives?

Consultant

What are some effective strategies for weight loss that have worked for you? Share your tips and experiences!

Best Weight Loss Strategies?

Software Engineer

Do mention where do you buy from as well.

Are you obese or diabetic ? If yes, what are some of the most common products / services you buy on a regular basis ?

Welcome to Office Gossip's Private Community

I'm addicted to having tea everyday to the point I get withdrawal symptoms if I miss

Non sweet tea irks me, but processed sugar is not good

Can you suggest alternatives? "Healthy"

Google suggested honey 😒 dumb
Also me don't like cinnamon, so that option gone

Sugar alternatives in milk tea?

What are some medical related stuffs, hacks, facts, less known info, your go to meds, must to have devices or equipments etc? 
I'll go first

- Have Paracetamol for fever, cold, weakness etc
- I have an oximeter/thermometer at home, any other must to have kits?
- Have a common wheelchair in the apartment for emergencies.
- Want common AED device as well in an apartment but it's too expensive over 1 Lakh .
- Always buy substitute medicine from other less known manufacturers with the same prescribed drugs, always up to 50% cheaper.

What else?

Medical Preparedness 101: Essential Meds, Devices, Facts and Hacks?

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Hello Grapevine
I am drinking massive amounts of iced black coffee and green tea simultaneously as a way to keep wired.
Modafinil and Nicotine gum to stay alert when busy along with Alpha GPC.

What Are Your Cognitive Enhancers?

Frontend Engineer

Alcohol, tobacco, medicines and drugs are rudimentary forms of biohacking : change my mind

Generalist

Hi guys so finally went to psychiatrist he prescribed me some medications. I am just worried about its side effects.

And i have habit of overthinking in worst case scenario. 

Not sure what to do.

Went to psychiatrist. Just nervous about side effects if any?

I hate how the Spotify app works now. Without premium you cannot listen to songs in your playlist in the order you want, you can't play the previous song, you cannot move the duration bar either.

However, I recently realised that if you listen to Spotify in a web browser, you get all the above perks without premium, and if you have a good as blocker, even the ads don't disturb you. Did you know this?

What are some other hacks that people generally don't know?

What are some life hacks that people generally don't know?

Application Engineer

Only in India will someone speaking scientific fact and sense against age-old myths can get banned by court orders on X

Only in India

He is not balanced. He extrapolates medical terminology to prove his point. There are frauds everywhere but he is no saint either. Good riddiance

Product Head

Hey guys,

My current weight is 83KG, 5'10" 23yo. My goal is to lose weight, and keep the weight within 73 to 75 kg range, in next 3 months.

I got a cultFit subscription from my company. There are too many things in cult fit. I am confused about what would be better for me. 

Should I go for HRX, Burn, Boxing or Normal Gym with personal trainer?

How to lose weight

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Work/Life/Play/Sleep whatever.

Noticing a massive improvement in sleep quality after getting all black sun blocking curtains. Especially considering the stress from work that is making me die on the inside, getting some sleep is a respite.

[Thread] What are some things to invest outside of financial assets that you invest in?

A gym memberships or home gym or something towards your physical health. No matter how healthy you are, your body needs to be more active since we spend most of our time sitting.

Hi guys,
Both me and my wife weight between 100-105 kg. Oru baby is 1 year old. We want to loose weight but we can hardly access gym due to tight schedule. We both have fatty liver , wife has got gall bladder stone and she is a feeding mother.

We want to reach first milestone around 80-85 kg which was out weight 2 years back.

Is there any free app to plan and guide weightloss. We heard like calorie deficit diet can help. Also cutting down the sugar and junk food.

Any thoughts?

Obesity Drugs: Miracle Cure or Overhyped Solution?

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